Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables insulin receptor binding activity and signaling receptor complex adaptor activity. Involved in several processes, including negative regulation of D-glucose import; negative regulation of signal transduction; and positive regulation of cold-induced thermogenesis. Acts upstream of or within with a negative effect on ERK1 and ERK2 cascade and gene expression. Acts upstream of or within insulin-like growth factor receptor signaling pathway and vascular associated smooth muscle cell migration. Predicted to be located in cytosol. Predicted to be part of protein-containing complex. Is expressed in several structures, including central nervous system; extraembryonic component; genitourinary system; musculoskeletal system; and sensory organ. Orthologous to human GRB10 (growth factor receptor bound protein 10).

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Gene Ontology Evidence Code Abbreviations:

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