Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including abducens nerve formation; cornified envelope assembly; and negative regulation of osteoclast differentiation. Acts upstream of or within several processes, including T cell differentiation in thymus; brain development; and thymus development. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Used to study Duane retraction syndrome and multicentric carpotarsal osteolysis syndrome. Human ortholog(s) of this gene implicated in Duane retraction syndrome and multicentric carpotarsal osteolysis syndrome. Orthologous to human MAFB (MAF bZIP transcription factor B).
This site uses cookies.
Some cookies are essential for site operations and others help us analyze use and utility of our web site.
Please refer to our
privacy policy
for more information.