Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.5.0)

Enables N-acetylglucosamine deacetylase activity; [heparan sulfate]-glucosamine N-sulfotransferase activity; and heparan sulfate N-deacetylase activity. Involved in heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process. Acts upstream of or within several processes, including circulatory system development; embryonic cranial skeleton morphogenesis; and positive regulation of signal transduction. Is active in Golgi apparatus. Is expressed in several structures, including alimentary system; future brain; integumental system; nervous system; and respiratory system. Used to study DiGeorge syndrome; congenital diaphragmatic hernia; and newborn respiratory distress syndrome. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 46. Orthologous to human NDST1 (N-deacetylase and N-sulfotransferase 1).

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Gene Ontology Evidence Code Abbreviations:

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