Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables cAMP-dependent protein kinase inhibitor activity and protein kinase A catalytic subunit binding activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; cellular response to glucagon stimulus; and positive regulation of insulin secretion. Acts upstream of or within several processes, including cardiac muscle cell proliferation; negative regulation of protein kinase activity; and sarcomere organization. Located in several cellular components, including centrosome; multivesicular body; and sperm head-tail coupling apparatus. Part of cAMP-dependent protein kinase complex. Is active in cytosol and glutamatergic synapse. Is expressed in several structures, including brain; branchial arch; ganglia; sensory organ; and tooth. Used to study Carney complex; acrodysostosis; follicular thyroid carcinoma; and primary pigmented nodular adrenocortical disease. Human ortholog(s) of this gene implicated in Carney complex; acrodysostosis; and primary pigmented nodular adrenocortical disease 1. Orthologous to human PRKAR1A (protein kinase cAMP-dependent type I regulatory subunit alpha).

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Gene Ontology Evidence Code Abbreviations:

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