Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables protein serine/threonine kinase activity. Involved in generation of neurons and mitotic cell cycle. Acts upstream of or within several processes, including dendrite development; metaphase/anaphase transition of mitotic cell cycle; and negative regulation of dendrite morphogenesis. Located in actin cytoskeleton; ruffle; and vacuole. Is expressed in several structures, including central nervous system; hemolymphoid system gland; respiratory system; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 17 and primary microcephaly. Orthologous to human CIT (citron rho-interacting serine/threonine kinase).
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