Automated description from the Alliance of Genome Resources (Release 7.5.0)
A structural constituent of ribosome. Involved in DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; cellular response to ionizing radiation; and positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in 1-cell stage embryo; 2-cell stage embryo; and 4-cell stage embryo. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 11. Orthologous to human RPL26 (ribosomal protein L26).
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