Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables netrin receptor binding activity. Involved in axon guidance and netrin-activated signaling pathway. Located in several cellular components, including filopodium; growth cone; and lamellipodium. Is expressed in several structures, including alimentary system; cardiovascular system; integumental system; nervous system; and sensory organ. Used to study congenital fibrosis of the extraocular muscles. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 1 and congenital fibrosis of the extraocular muscles 3A. Orthologous to human TUBB3 (tubulin beta 3 class III).
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