Automated description from the Alliance of Genome Resources (Release 8.0.0)
Enables lipoprotein particle binding activity; lipoteichoic acid immune receptor activity; and low-density lipoprotein particle receptor activity. Involved in several processes, including negative regulation of macromolecule biosynthetic process; positive regulation of intracellular signal transduction; and positive regulation of metabolic process. Acts upstream of or within several processes, including phagocytosis; positive regulation of cytokine production; and response to bacterium. Located in several cellular components, including brush border membrane; external side of plasma membrane; and membrane raft. Is expressed in several structures, including axial skeleton; bone; connective tissue; hindlimb; and telencephalon. Used to study platelet-type bleeding disorder 10. Human ortholog(s) of this gene implicated in several diseases, including blood platelet disease (multiple); hemolytic-uremic syndrome; osteoarthritis; pulmonary tuberculosis; and type 2 diabetes mellitus. Orthologous to human CD36 (CD36 molecule (CD36 blood group)).
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