Automated description from the Alliance of Genome Resources (Release 7.2.0)
Enables protein-macromolecule adaptor activity. Involved in canonical Wnt signaling pathway and non-canonical Wnt signaling pathway. Acts upstream of or within cochlea morphogenesis; outflow tract septum morphogenesis; and planar cell polarity pathway involved in neural tube closure. Located in cytoplasm. Part of Wnt signalosome. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; eye; and genitourinary system. Human ortholog(s) of this gene implicated in autosomal dominant Robinow syndrome 3 and lung cancer. Orthologous to human DVL3 (dishevelled segment polarity protein 3).
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