Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including PERK-mediated unfolded protein response; positive regulation of biosynthetic process; and regulation of reactive oxygen species metabolic process. Acts upstream of or within several processes, including cellular response to copper ion; endoplasmic reticulum unfolded protein response; and positive regulation of DNA-templated transcription. Located in chromatin; cytosol; and nucleus. Part of protein-DNA complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease; cataract; hepatocellular carcinoma; macular degeneration; and tuberculosis. Orthologous to human NFE2L2 (NFE2 like bZIP transcription factor 2).

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Gene Ontology Evidence Code Abbreviations:

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