Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables phosphatidylinositol 3-kinase activator activity; phosphatidylinositol 3-kinase binding activity; and transmembrane receptor protein tyrosine kinase adaptor activity. Involved in several processes, including insulin receptor signaling pathway; positive regulation of B cell proliferation; and positive regulation of cell communication. Acts upstream of or within several processes, including cellular response to insulin stimulus; positive regulation of cell population proliferation; and positive regulation of epithelial cell migration. Located in cytosol and plasma membrane. Is expressed in several structures, including brain ventricular layer; hindlimb digit skin; jaw; metanephros; and thymus primordium. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human IRS2 (insulin receptor substrate 2).

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Gene Ontology Evidence Code Abbreviations:

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