Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.5.0)

Enables several functions, including calcium channel regulator activity; calcium-dependent protein binding activity; and signaling receptor binding activity. Involved in several processes, including modulation of chemical synaptic transmission; regulation of synapse assembly; and synapse organization. Acts upstream of or within neurotransmitter secretion; positive regulation of synapse assembly; and positive regulation of synapse maturation. Located in several cellular components, including axonal growth cone; neuronal cell body; and nuclear membrane. Part of protein complex involved in cell-cell adhesion and trans-synaptic protein complex. Is active in several cellular components, including GABA-ergic synapse; Schaffer collateral - CA1 synapse; and presynaptic active zone membrane. Is expressed in several structures, including adrenal gland; limb; nervous system; oral epithelium; and sensory organ. Used to study autism spectrum disorder and schizophrenia. Human ortholog(s) of this gene implicated in Pitt-Hopkins-like syndrome 2. Orthologous to human NRXN1 (neurexin 1).

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Gene Ontology Evidence Code Abbreviations:

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