Automated description from the Alliance of Genome Resources (Release 7.2.0)
Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; RNA polymerase II core promoter sequence-specific DNA binding activity; and nucleosomal DNA binding activity. Predicted to be a structural constituent of chromatin. Involved in oocyte maturation. Acts upstream of or within several processes, including constitutive heterochromatin formation; negative regulation of chromosome condensation; and osteoblast differentiation. Located in Barr body. Part of chromatin and inner kinetochore. Is active in chromosome, centromeric region. Is expressed in several structures, including central nervous system; gonad; heart; hemolymphoid system gland; and retina. Orthologous to human H3-3A (H3.3 histone A) and H3-3B (H3.3 histone B).
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