Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables kinetochore binding activity and protein kinase binding activity. Involved in several processes, including attachment of spindle microtubules to kinetochore; positive regulation of protein kinase activity; and regulation of chromosome segregation. Acts upstream of or within regulation of protein stability and spindle assembly involved in female meiosis I. Located in kinetochore. Part of outer kinetochore. Is expressed in dentate gyrus subgranular zone; testis; and thymus. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 13. Orthologous to human CENPE (centromere protein E).
This site uses cookies.
Some cookies are essential for site operations and others help us analyze use and utility of our web site.
Please refer to our
privacy policy
for more information.