Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within heart development and kidney development. Predicted to be located in aggresome; cytosol; and nucleolus. Predicted to be active in nucleoplasm. Is expressed in central nervous system and ureter. Orthologous to human ZBTB14 (zinc finger and BTB domain containing 14).
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