Automated description from the Alliance of Genome Resources (Release 7.2.0)
Enables kinase binding activity. Involved in several processes, including negative regulation of cytokine production; negative regulation of defense response; and negative regulation of signal transduction. Acts upstream of or within establishment of protein localization to vacuole and positive regulation of protein catabolic process. Located in cytoplasm. Is expressed in central nervous system; genitourinary system; heart; and retina. Human ortholog(s) of this gene implicated in breast cancer; colorectal cancer; esophageal cancer; and familial Behcet-like autoinflammatory syndrome. Orthologous to human TNFAIP3 (TNF alpha induced protein 3).
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