Go Annotations as Summary Text (Tabular View) (GO Graph)

---

Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates; DNA binding activity; and lncRNA binding activity. Involved in negative regulation of gene expression, epigenetic. Acts upstream of or within several processes, including cellular response to amino acid stimulus; epigenetic regulation of gene expression; and negative regulation of transcription by RNA polymerase II. Located in chromosome, centromeric region; heterochromatin; and nucleus. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and hemolymphoid system. Used to study immunodeficiency-centromeric instability-facial anomalies syndrome 1. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); facioscapulohumeral muscular dystrophy 4; immunodeficiency-centromeric instability-facial anomalies syndrome 1; and thymoma. Orthologous to human DNMT3B (DNA methyltransferase 3 beta).

---

---

---

Gene Ontology Evidence Code Abbreviations:

---