Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding activity; and chromatin DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including negative regulation of neuroblast proliferation; nervous system development; and skeletal muscle cell differentiation. Located in nucleus. Is expressed in several structures, including embryo ectoderm; gonad; nervous system; oral epithelium; and sensory organ. Human ortholog(s) of this gene implicated in syndromic microphthalmia 11. Orthologous to human VAX1 (ventral anterior homeobox 1).

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Gene Ontology Evidence Code Abbreviations:

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