Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables cell adhesion molecule binding activity. Involved in several processes, including cell-cell adhesion mediated by cadherin; pore complex assembly; and regulation of postsynapse assembly. Acts upstream of or within several processes, including adherens junction maintenance; nervous system development; and regulation of oligodendrocyte progenitor proliferation. Located in several cellular components, including adherens junction; apical junction complex; and apical part of cell. Part of pore complex. Is active in hippocampal mossy fiber to CA3 synapse; postsynaptic density membrane; and presynaptic active zone membrane. Is expressed in central nervous system; dorsal root ganglion; eye; and genitourinary system. Orthologous to human AFDN (afadin, adherens junction formation factor).
This site uses cookies.
Some cookies are essential for site operations and others help us analyze use and utility of our web site.
Please refer to our
privacy policy
for more information.