Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables DNA-binding transcription activator activity; chromatin binding activity; and transcription cis-regulatory region binding activity. Involved in transcription initiation-coupled chromatin remodeling. Acts upstream of or within several processes, including negative regulation of cell population proliferation; regulation of gene expression; and regulation of osteoblast differentiation. Located in chromosome, telomeric region; cytoplasm; and nucleus. Is expressed in several structures, including 1st branchial arch; alimentary system; central nervous system; gonad; and sensory organ. Used to study growth hormone secreting pituitary adenoma; hyperparathyroidism; multiple endocrine neoplasia type 1; and prolactinoma. Human ortholog(s) of this gene implicated in endocrine gland cancer (multiple); hyperparathyroidism; and multiple endocrine neoplasia type 1. Orthologous to human MEN1 (menin 1).

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Gene Ontology Evidence Code Abbreviations:

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