Automated description from the Alliance of Genome Resources (Release 8.0.0)
Enables alanine-glyoxylate transaminase activity. Acts upstream of or within Notch signaling pathway; glyoxylate metabolic process; and oxalic acid secretion. Predicted to be located in mitochondrial matrix and peroxisomal matrix. Predicted to be active in peroxisome. Is expressed in liver. Used to study primary hyperoxaluria type 1. Human ortholog(s) of this gene implicated in primary hyperoxaluria type 1. Orthologous to human AGXT (alanine--glyoxylate aminotransferase).
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