Automated description from the Alliance of Genome Resources (Release 7.2.0)
Predicted to enable several functions, including ATP binding activity; magnesium ion binding activity; and nuclear estrogen receptor binding activity. Involved in hormone-mediated signaling pathway; negative regulation of protein localization to nucleus; and regulation of transforming growth factor beta receptor signaling pathway. Acts upstream of or within several processes, including hippo signaling; inner cell mass cell differentiation; and keratinocyte differentiation. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be active in spindle pole. Is expressed in several structures, including central nervous system; early conceptus; lung; and otocyst. Orthologous to human LATS1 (large tumor suppressor kinase 1).
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