Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and beta-catenin binding activity. Involved in neuron differentiation; positive regulation of canonical Wnt signaling pathway; and regulation of transcription by RNA polymerase II. Acts upstream of or within negative regulation of neuron apoptotic process. Located in extracellular space. Is expressed in several structures, including central nervous system; future brain; and retina. Human ortholog(s) of this gene implicated in Helsmoortel-Van Der Aa Syndrome. Orthologous to human ADNP (activity dependent neuroprotector homeobox).
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