Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.5.0)

Predicted to enable several functions, including ATP binding activity; activin binding activity; and transmembrane receptor protein serine/threonine kinase activity. Involved in several processes, including circulatory system development; regulation of endothelial cell differentiation; and regulation of endothelial cell proliferation. Acts upstream of or within several processes, including angiogenesis; positive regulation of angiogenesis; and transforming growth factor beta receptor superfamily signaling pathway. Predicted to be located in cell surface; dendrite; and neuronal cell body. Predicted to be part of BMP receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and immune system. Used to study arteriovenous malformations of the brain; hereditary hemorrhagic telangiectasia; and obstructive nephropathy. Human ortholog(s) of this gene implicated in hereditary hemorrhagic telangiectasia and pulmonary hypertension. Orthologous to human ACVRL1 (activin A receptor like type 1).

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Gene Ontology Evidence Code Abbreviations:

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