Automated description from the Alliance of Genome Resources (Release 7.4.0)
A structural constituent of postsynaptic density. Involved in several processes, including axo-dendritic protein transport; clustering of voltage-gated potassium channels; and neurotransmitter receptor localization to postsynaptic specialization membrane. Acts upstream of or within chemical synaptic transmission and sensory perception of pain. Located in several cellular components, including juxtaparanode region of axon; postsynaptic membrane; and synaptic vesicle membrane. Is active in axon initial segment and glutamatergic synapse. Is expressed in jaw bone; nervous system; and retina. Orthologous to human DLG2 (discs large MAGUK scaffold protein 2).
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