Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables iron ion transmembrane transporter activity; manganese ion transmembrane transporter activity; and metal cation:proton antiporter activity. Involved in iron ion transport and manganese ion transport. Acts upstream of or within several processes, including defense response to other organism; intracellular monoatomic cation homeostasis; and regulation of gene expression. Located in late endosome membrane; lysosomal membrane; and phagocytic vesicle membrane. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in several diseases, including Buruli ulcer disease; autoimmune disease (multiple); inflammatory bowel disease (multiple); leishmaniasis (multiple); and tuberculosis (multiple). Orthologous to human SLC11A1 (solute carrier family 11 member 1).

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Gene Ontology Evidence Code Abbreviations:

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