Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables actin filament binding activity and identical protein binding activity. Acts upstream of or within several processes, including early endosome to recycling endosome transport; nerve growth factor signaling pathway; and regulation of organelle organization. Located in several cellular components, including cell leading edge; early endosome; and immunological synapse. Is active in glutamatergic synapse and stereocilium tip. Is expressed in several structures, including alimentary system; hemolymphoid system; male reproductive gland or organ; nervous system; and respiratory system. Used to study severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Human ortholog(s) of this gene implicated in coronin-1A deficiency. Orthologous to human CORO1A (coronin 1A).
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