Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Predicted to enable beta-catenin binding activity; gamma-catenin binding activity; and microtubule binding activity. Predicted to be involved in several processes, including activation of GTPase activity; negative regulation of canonical Wnt signaling pathway; and negative regulation of microtubule depolymerization. Predicted to be located in several cellular components, including cytoskeleton; lamellipodium membrane; and midbody. Predicted to be part of beta-catenin destruction complex; catenin complex; and filamentous actin. Predicted to be active in postsynapse. Predicted to colocalize with cytoplasmic microtubule. Is expressed in several structures, including appendicular skeleton; axial skeleton; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Sotos syndrome 3; autosomal recessive intellectual developmental disorder 74; and complex cortical dysplasia with other brain malformations. Orthologous to human APC2 (APC regulator of WNT signaling pathway 2).

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Gene Ontology Evidence Code Abbreviations:

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