Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables several functions, including amyloid-beta binding activity; lipopeptide binding activity; and lipoteichoic acid binding activity. Involved in several processes, including microglia development; negative regulation of cellular component organization; and positive regulation of macromolecule biosynthetic process. Acts upstream of or within several processes, including positive regulation of defense response; regulation of cytokine production; and response to bacterium. Located in external side of plasma membrane. Part of Toll-like receptor 2-Toll-like receptor 6 protein complex. Is expressed in several structures, including brain; early embryo; genitourinary system; gut; and immune system. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dermatitis (multiple); gastrointestinal system cancer (multiple); lung disease (multiple); and rhinitis (multiple). Orthologous to human TLR2 (toll like receptor 2).

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Gene Ontology Evidence Code Abbreviations:

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