Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.5.0)

Enables MAP kinase kinase activity; MAP kinase kinase kinase kinase activity; and receptor tyrosine kinase binding activity. Involved in several processes, including anoikis; negative regulation of necroptotic process; and positive regulation of canonical NF-kappaB signal transduction. Acts upstream of or within several processes, including intracellular signaling cassette; regulation of signal transduction; and tube morphogenesis. Located in postsynaptic density. Is expressed in several structures, including brain; gut; male reproductive gland or organ; metanephros; and respiratory system. Used to study Wolff-Parkinson-White syndrome. Human ortholog(s) of this gene implicated in frontometaphyseal dysplasia; frontometaphyseal dysplasia 2; and prostate cancer. Orthologous to human MAP3K7 (mitogen-activated protein kinase kinase kinase 7).

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Gene Ontology Evidence Code Abbreviations:

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