Automated description from the Alliance of Genome Resources (Release 7.2.0)
Enables DEAD/H-box RNA helicase binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in cellular response to granulocyte macrophage colony-stimulating factor stimulus and negative regulation of cell population proliferation. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Part of RNA polymerase II transcription repressor complex and chromatin. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; retina; and thymus primordium. Orthologous to human ETV3 (ETS variant transcription factor 3).
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