Automated description from the Alliance of Genome Resources (Release 7.4.0)
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including nervous system development; regulation of respiratory gaseous exchange by nervous system process; and respiratory gaseous exchange by respiratory system. Located in nucleus. Is expressed in several structures, including branchial arch; central nervous system; ganglia; genitourinary system; and sensory organ. Used to study congenital central hypoventilation syndrome. Orthologous to human TLX3 (T cell leukemia homeobox 3).
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