Automated description from the Alliance of Genome Resources (Release 7.3.0)
Enables RNA binding activity and transcription corepressor activity. Involved in negative regulation of DNA-templated transcription. Acts upstream of or within several processes, including adrenal gland development; endodermal cell differentiation; and male gonad development. Located in cytoplasm; nucleus; and ribosome. Is expressed in several structures, including adrenal gland; branchial arch; central nervous system; early conceptus; and genitourinary system. Used to study X-linked adrenal hypoplasia congenita. Human ortholog(s) of this gene implicated in 46,XY sex reversal 2 and X-linked adrenal hypoplasia congenita. Orthologous to human NR0B1 (nuclear receptor subfamily 0 group B member 1).
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