Automated description from the Alliance of Genome Resources (Release 7.2.0)
Enables small GTPase binding activity. Involved in cell surface receptor protein tyrosine kinase signaling pathway; cellular response to epidermal growth factor stimulus; and cellular response to platelet-derived growth factor stimulus. Acts upstream of or within fibroblast migration; negative regulation of dephosphorylation; and regulation of cytokine production. Located in several cellular components, including basolateral plasma membrane; focal adhesion; and lateral plasma membrane. Part of ribonucleoprotein complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and hemolymphoid system gland. Orthologous to human IQGAP1 (IQ motif containing GTPase activating protein 1).
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