Automated description from the Alliance of Genome Resources (Release 7.5.0)
Enables 1-phosphatidylinositol-3-kinase activity. Involved in several processes, including G protein-coupled receptor signaling pathway; phosphatidylinositol 3-kinase/protein kinase B signal transduction; and positive regulation of Rac protein signal transduction. Acts upstream of or within several processes, including cellular response to cAMP; negative regulation of fibroblast apoptotic process; and protein phosphorylation. Predicted to be located in cytosol and membrane. Predicted to be part of phosphatidylinositol 3-kinase complex, class IA and phosphatidylinositol 3-kinase complex, class IB. Predicted to be active in cytoplasm and plasma membrane. Is expressed in future spinal cord; hemolymphoid system; and thymus primordium. Human ortholog(s) of this gene implicated in autistic disorder; primary immunodeficiency disease; and swine influenza. Orthologous to human PIK3CG (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma).
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