Automated description from the Alliance of Genome Resources (Release 7.2.0)
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and histone H3K36 demethylase activity. Involved in several processes, including brain development; embryonic morphogenesis; and negative regulation of neuron apoptotic process. Acts upstream of or within negative regulation of transcription by RNA polymerase II; positive regulation of cell growth; and positive regulation of stem cell population maintenance. Predicted to be located in nucleoplasm. Predicted to be part of PcG protein complex. Is expressed in several structures, including genitourinary system; lung; and telencephalon. Orthologous to human KDM2B (lysine demethylase 2B).
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