Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables several functions, including RNA polymerase II C-terminal domain binding activity; lysine-acetylated histone binding activity; and protein serine/threonine kinase activity. Involved in positive regulation of T-helper 17 cell lineage commitment. Acts upstream of or within chromosome segregation; inner cell mass cell proliferation; and protein autophosphorylation. Located in chromatin and condensed nuclear chromosome. Part of cyclin/CDK positive transcription elongation factor complex. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; liver; and sensory organ. Used to study nephrocalcinosis. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 6; colon cancer; and idiopathic pulmonary fibrosis. Orthologous to human BRD4 (bromodomain containing 4).

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Gene Ontology Evidence Code Abbreviations:

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