Automated description from the Alliance of Genome Resources (Release 7.5.0)
Predicted to enable transmembrane transporter binding activity. Involved in locomotory exploration behavior and negative regulation of large conductance calcium-activated potassium channel activity. Predicted to be located in nucleus and perinuclear region of cytoplasm. Predicted to be part of Cul4A-RING E3 ubiquitin ligase complex. Is expressed in several structures, including alimentary system; aorta; central nervous system; eye; and genitourinary system. Used to study autosomal recessive intellectual developmental disorder. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 2. Orthologous to human CRBN (cereblon).
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