Automated description from the Alliance of Genome Resources (Release 7.2.0)
Predicted to enable caspase binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including cellular response to organic cyclic compound; negative regulation of canonical NF-kappaB signal transduction; and regulation of innate immune response. Predicted to act upstream of or within defense response to virus; innate immune response; and ribosome biogenesis. Predicted to be located in cytoplasm. Predicted to be part of preribosome, small subunit precursor. Predicted to be active in cytosol. Is expressed in ganglia; sensory organ; trigeminal nerve; and vibrissa. Orthologous to human RIOK3 (RIO kinase 3).
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