Automated description from the Alliance of Genome Resources (Release 7.4.0)
Predicted to enable frizzled binding activity. Predicted to be involved in several processes, including positive regulation of epithelial to mesenchymal transition; regulation of signal transduction; and transforming growth factor beta receptor signaling pathway. Predicted to act upstream of or within negative regulation of BMP signaling pathway. Predicted to be located in cytoplasm and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human BAMBI (BMP and activin membrane bound inhibitor).
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