Automated description from the Alliance of Genome Resources (Release 7.4.0)
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including nodal signaling pathway; positive regulation of amacrine cell differentiation; and regulation of gastrulation. Predicted to be located in centrosome and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; forelimb phalanx; genitourinary system; and sensory organ. Orthologous to human TGIF2 (TGFB induced factor homeobox 2).
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