Automated description from the Alliance of Genome Resources (Release 7.4.0)
Predicted to enable GTP binding activity and GTPase activity. Involved in nervous system development; non-motile cilium assembly; and smoothened signaling pathway. Acts upstream of or within dorsal/ventral pattern formation; heart looping; and left/right axis specification. Located in axoneme; ciliary membrane; and motile cilium. Is expressed in several structures, including chordamesoderm; embryo mesenchyme; gonad; neural ectoderm; and node. Human ortholog(s) of this gene implicated in Joubert syndrome 8. Orthologous to human ARL13B (ADP ribosylation factor like GTPase 13B).
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