Automated description from the Alliance of Genome Resources (Release 7.2.0)
Enables chromatin binding activity and transcription cis-regulatory region binding activity. Involved in several processes, including dendritic transport of messenger ribonucleoprotein complex; negative regulation of DNA-templated transcription; and negative regulation of circadian rhythm. Acts upstream of or within DNA damage response; chromosome organization; and positive regulation of sister chromatid cohesion. Located in dendrite cytoplasm and paraspeckles. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; lung mesenchyme; sensory organ; and testis. Orthologous to human SFPQ (splicing factor proline and glutamine rich).
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