Automated description from the Alliance of Genome Resources (Release 7.2.0)
Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity; and lysine-acetylated histone binding activity. Involved in several processes, including cell dedifferentiation; positive regulation of transcription by RNA polymerase II; and regulation of stem cell division. Acts upstream of or within several processes, including negative regulation of BMP signaling pathway; negative regulation of cell differentiation; and response to retinoic acid. Located in nucleoplasm. Part of chromatin. Is expressed in several structures, including early conceptus; genitourinary system; gut; hemolymphoid system; and primitive streak. Orthologous to several human genes including NANOG (Nanog homeobox).
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