Automated description from the Alliance of Genome Resources (Release 7.5.0)
Predicted to be an extracellular matrix structural constituent. Involved in cell surface receptor protein serine/threonine kinase signaling pathway; regulation of protein localization; and ureteric bud development. Acts upstream of or within inner ear development and negative regulation of BMP signaling pathway. Located in extracellular region. Is expressed in several structures, including branchial arch; cardiovascular system; embryo mesenchyme; jaw; and neural ectoderm. Human ortholog(s) of this gene implicated in opiate dependence. Orthologous to human BMPER (BMP binding endothelial regulator).
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