Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables 1-phosphatidylinositol-3-kinase activity and insulin receptor substrate binding activity. Involved in several processes, including phosphatidylinositol 3-kinase/protein kinase B signal transduction; regulation of intracellular signal transduction; and response to ischemia. Acts upstream of or within several processes, including angiogenesis involved in wound healing; embryonic cleavage; and homophilic cell adhesion via plasma membrane adhesion molecules. Located in nucleus. Is expressed in several structures, including central nervous system; early embryo; genitourinary system; respiratory system; and spleen. Human ortholog(s) of this gene implicated in glioblastoma; prostate adenocarcinoma; prostate cancer; and type 2 diabetes mellitus. Orthologous to human PIK3CB (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta).

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Gene Ontology Evidence Code Abbreviations:

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