Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables NAD-dependent protein lysine deacetylase activity and sequence-specific DNA binding activity. Involved in peptidyl-lysine deacetylation; positive regulation of ceramide biosynthetic process; and positive regulation of mitochondrial transcription. Acts upstream of or within negative regulation of peptidyl-lysine acetylation and protein deacetylation. Located in mitochondrial inner membrane and mitochondrial matrix. Part of protein-containing complex. Is expressed in several structures, including brain; branchial arch; endocrine gland; genitourinary system; and liver and biliary system. Used to study abdominal obesity-metabolic syndrome. Orthologous to human SIRT3 (sirtuin 3).

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Gene Ontology Evidence Code Abbreviations:

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