Automated description from the Alliance of Genome Resources (Release 7.2.0)
Enables protein homodimerization activity. Involved in establishment of protein localization to plasma membrane; homophilic cell adhesion via plasma membrane adhesion molecules; and regulation of postsynapse assembly. Acts upstream of or within several processes, including camera-type eye morphogenesis; fertilization; and protein localization to cell junction. Located in several cellular components, including adherens junction; apical junction complex; and cell-cell contact zone. Is active in hippocampal mossy fiber to CA3 synapse and postsynaptic density membrane. Is expressed in several structures, including metanephros; nervous system; sensory organ; skeletal musculature; and tooth. Orthologous to human NECTIN3 (nectin cell adhesion molecule 3).
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