Automated description from the Alliance of Genome Resources (Release 7.4.0)
Predicted to enable several functions, including DNA binding activity; chromatin binding activity; and transcription coactivator activity. Involved in several processes, including intracellular glucose homeostasis; positive regulation of transcription by RNA polymerase II; and regulation of insulin receptor signaling pathway. Acts upstream of or within glucose homeostasis and positive regulation of insulin receptor signaling pathway. Located in chromatin; cytoplasm; and nucleus. Is expressed in central nervous system; embryo; liver; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human NUCKS1 (nuclear casein kinase and cyclin dependent kinase substrate 1).
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