Automated description from the Alliance of Genome Resources (Release 7.4.0)
Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; SUMO ligase activity; and transcription corepressor activity. Predicted to be involved in negative regulation of transcription initiation by RNA polymerase II; negative regulation of transforming growth factor beta receptor signaling pathway; and protein sumoylation. Predicted to be located in PML body. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; early conceptus; gonad; and metanephros. Orthologous to human ZNF451 (zinc finger protein 451).
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